Imputation in genome-wide association analysis [electronic resource] / Jonathan Marchini.
Material type:
FilmPublisher number: 4318 | Henry Stewart TalksSeries: Henry Stewart talks. Biomedical & life sciences collection. Statistical genetics. | Henry Stewart talks. Biomedical & life sciences collection. Statistical methods for the analysis of genome-wide association studies : practical advice and guidance.Publication details: London : Henry Stewart Talks, 2017.Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): - Algorithms
- Bioinformatics
- Genetics -- Statistical methods
- Medical genetics
- Population genetics
- Biostatistics -- methods
- Datasets as Topic
- Genetic techniques
- Genetics, Medical
- Genome-Wide Association Study
- Genomics -- statistics & numerical data
- Haplotypes
- Models, Genetic
- Polymorphism, Single Nucleotide
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The general problem of imputation -- Testing imputed SNPs for association -- Examples of imputation in the WTCCC -- Properties of imputation (LD, populations, chips, allele frequency) -- Using imputed data for meta-analysis -- The Strand Issue and Imputation QC metrics -- The 1000 Genomes Project -- Pre-phasing and haplotype estimation -- The Haplotype Reference Consortium.
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Mode of access: World Wide Web.
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