Arylamine N-acetyltransferases [electronic resource] : part 2 of 3 / Edith Sim.
Material type:
FilmPublisher number: 4278 | Henry Stewart TalksSeries: Henry Stewart talks. Biomedical & life sciences collection. Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance.Publication details: London : Henry Stewart Talks, 2016.Description: 1 online resource (1 streaming video file (23 min.) : color, sound)Other title: - Arylamine N-acetyltransferases 2
- Antibacterial agents
- Biochemical markers
- Breast -- Cancer
- Drug development
- Drugs -- Metabolism
- Enzyme Inhibitors
- Isoenzymes
- Transferases
- Antitubercular Agents
- Arylamine N-Acetyltransferase -- antagonists & inhibitors
- Arylamine N-Acetyltransferase -- genetics
- Arylamine N-Acetyltransferase -- metabolism
- Bacterial Infections -- drug therapy
- Biomarkers
- Breast Neoplasms -- diagnosis
- Drug Discovery -- methods
- Enzyme Inhibitors -- pharmacology
- Ethnic Groups
- Gene Expression Regulation, Enzymologic
- Genetic Association Studies
- Isoenzymes -- metabolism
- Mice, Transgenic
- Mycobacterium -- drug effects
- Pharmaceutical Preparations -- metabolism
- Pharmacogenetics
Animated audio-visual presentation with synchronized narration.
Revised version of a talk first published in 2007.
Title from title frames.
Contents: Mechanism of action -- Reaction substrates -- Isoform substrate profiles -- Isoenzymes NAT1 and NAT2 -- Regulation of gene expression -- Pharmacogenetics -- Phenotype/genotype correlation -- Ethnic variation -- Transgenic mouse models -- NAT protein structures -- NAT as a biomarker in breast cancer -- NAT inhibitors as diagnostic agents -- NAT in mycobacteria -- NAT inhibitors as an approach to potential anti-tubercular agents.
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Mode of access: World Wide Web.
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