Structure and activation of endothelin ETB receptor by endothelin [electronic resource] / Tomoko Doi.
Material type:
FilmPublisher number: 4779 | Henry Stewart TalksSeries: Henry Stewart talks. Biomedical & life sciences collection. Structural and functional insights into GPCR signalling: Publication details: London : Henry Stewart Talks, 2019.Description: 1 online resource (1 streaming video file (26 min.) : color, sound)Subject(s): - Cellular signal transduction
- Endothelins -- Physiological effect
- Endothelins -- Receptors
- G proteins -- Receptors
- Bosentan
- Endothelin-1 -- chemistry
- Endothelin-1 -- metabolism
- Endothelin-1 -- pharmacology
- Ligands
- Protein Conformation
- Receptor, Endothelin B -- chemistry
- Receptor, Endothelin B -- metabolism
- Receptors, Endothelin
- Receptors, G-Protein-Coupled
- Signal Transduction
- Vasoconstriction -- drug effects
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Background to endothelin, ET(A) and ET(B) -- Endothelin and peptide GPCR -- Vasoactive and mitogen-like peptide -- Thermostabilization of ET(B) -- Structures of ET-1-bound and bosentan-bound ET(B) receptor -- Ligand recognition and conformational changes of ET(B) for signal transduction.
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Mode of access: World Wide Web.
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