TNF superfamily cytokines and receptors in the healthy and diseased immune system [electronic resource] / Richard M. Siegel.
Material type:
FilmPublisher number: 3095 | Henry Stewart TalksSeries: Henry Stewart talks. Biomedical & life sciences collection. Cytokines.Publication details: London : Henry Stewart Talks, 2011.Description: 1 online resource (1 streaming video file (29 min.) : color, sound)Subject(s): - Autoimmunity
- B cells -- Immunology
- Osteoclasts
- T cells -- Immunology
- Tumor necrosis factor -- Receptors
- Tumor necrosis factor
- Cytokines -- immunology
- Fas-Associated Death Domain Protein
- Gene Expression
- Immunity, Innate
- Osteoclasts
- Receptors, Tumor Necrosis Factor
- Signal Transduction
- Tumor Necrosis Factor-alpha
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Genomics of the TNF/TNFR superfamily -- TNF/TNFR signaling types -- Various domains of TNFR -- TNF ligands and receptor binding -- Fas and the TNFR family -- Apoptosis through DISC recruitment -- FAS-FADD crystal structure -- Gene expression through TRAF proteins and regulation by dynamic expression of ligands -- Lymph node development -- Innate immunity enhancement -- B & T cells and the TNFR superfamily -- Multiple programmed cell death pathways -- Osteoclast development -- Molecular mechanisms of genetic diseases and defects in the Fas pathway -- Fas intra and extracellular mutations -- Therapeutics and anti-inflammatory uses of TNF superfamily blockade.
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Mode of access: World Wide Web.
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