Mitochondria and calcium signaling in cell life and cell death [electronic resource] / Michael R. Duchen.

By: Material type: FilmFilmPublisher number: 4513 | Henry Stewart TalksSeries: Henry Stewart talks. Biomedical & life sciences collection. Mitochondria in health and disease.Publication details: London : Henry Stewart Talks, 2018.Description: 1 online resource (1 streaming video file (39 min.) : color, sound)Subject(s): Online resources:
Contents:
Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target.
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Animated audio-visual presentation with synchronized narration.

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Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target.

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