TY  - BOOK
AU  - Boverhof,Darrell R.
AU  - Gollapudi,B.Bhaskar
ED  - ebrary, Inc.
TI  - Applications of toxicogenomics in safety evaluation and risk assessment
AV  - RA1224.3 .B68 2011eb
U1  - 616/.042 22
PY  - 2011///
CY  - Hoboken, N.J.
PB  - John Wiley & Sons
KW  - Genetic toxicology
KW  - Toxicity testing
KW  - Health risk assessment
KW  - Electronic books
KW  - local
N1  - Includes bibliographical references and index; Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach; Electronic reproduction; Palo Alto, Calif.; ebrary; 2011; Available via World Wide Web; Access may be limited to ebrary affiliated libraries
UR  - http://site.ebrary.com/lib/daystar/Doc?id=10494674
ER  -