TY  - BOOK
AU  - Peters,Sheila Annie
ED  - ebrary, Inc.
TI  - Physiologically-based pharmacokinetic (PBPK) modeling and simulations: principles, methods, and applications in the pharmaceutical industry 
AV  - RM301.5 .P48 2011eb
U1  - 615/.7 23
PY  - 2011///
CY  - Hoboken, N.J.
PB  - Wiley
KW  - Pharmacokinetics
KW  - Mathematical models
KW  - Drugs
KW  - Design
KW  - Electronic books
KW  - local
N1  - Includes bibliographical references and index; Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain; Electronic reproduction; Palo Alto, Calif.; ebrary; 2011; Available via World Wide Web; Access may be limited to ebrary affiliated libraries
UR  - http://site.ebrary.com/lib/daystar/Doc?id=10558150
ER  -