Sugano, Kiyohiko. <br/><br/>
Biopharmaceutics modeling and simulations  theory, practice, methods, and applications /  [electronic resource] : 
Kiyohiko Sugano. 
 - Hoboken, N.J. :  Wiley,  c2012. 
 - xxxv, 483 p. :  ill. 
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice. 
<br/><br/><br/>Electronic reproduction. <br/>Palo Alto, Calif. : <br/>ebrary, <br/>2011. <br/>Available via World Wide Web. <br/>Access may be limited to ebrary affiliated libraries. 
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<br/><br/><label>Subjects--Topical Terms: </label><br/>Biopharmaceutics--Simulation methods.<br/>Computer simulation.
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>RM301.4  / .S84 2012eb 
<br/><br/><label>Dewey Class. No.: </label>615.7