TY - BOOK AU - Sugano,Kiyohiko ED - ebrary, Inc. TI - Biopharmaceutics modeling and simulations: theory, practice, methods, and applications AV - RM301.4 .S84 2012eb U1 - 615.7 23 PY - 2012/// CY - Hoboken, N.J. PB - Wiley KW - Biopharmaceutics KW - Simulation methods KW - Computer simulation KW - Electronic books KW - local N1 - Includes bibliographical references and index; Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice; Electronic reproduction; Palo Alto, Calif.; ebrary; 2011; Available via World Wide Web; Access may be limited to ebrary affiliated libraries UR - http://site.ebrary.com/lib/daystar/Doc?id=10583403 ER -