Crichton, Robert R.

Metal-based neurodegeneration : from molecular mechanisms to therapeutic strategies / Robert Crichton and Roberta Ward. - Second edition. - 1 online resource (469 pages) : illustrations

Includes bibliographical references and index.

Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases.




Brain--Pathophysiology.
Metals--Health aspects.
Nervous system--Degeneration--Etiology.
Oxidative stress.


Electronic books.

RC365 / .C75 2014eb

616.8/0471