TY  - BOOK
AU  - Roterman,Irena
AU  - Konieczny,Leszek
ED  - SpringerLink (Online service)
TI  - Self-Assembled Molecules – New Kind of Protein Ligands: Supramolecular Ligands 
SN  - 9783319656397
AV  - R-RZ 
U1  - 610 23
PY  - 2018///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Medicine
KW  - Proteins
KW  - Biology
KW  - Technique
KW  - Biomedicine
KW  - Biomedicine general
KW  - Protein Science
KW  - Protein-Ligand Interactions
KW  - Biological Techniques
N1  - Open Access
N2  - This book is an open access under a CC BY license.  The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book
UR  - http://dx.doi.org/10.1007/978-3-319-65639-7
ER  -