Doi, Tomoko,

Structure and activation of endothelin ETB receptor by endothelin [electronic resource] / Tomoko Doi. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (26 min.) : color, sound). - Structural and functional insights into GPCR signalling, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Structural and functional insights into GPCR signalling: .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Background to endothelin, ET(A) and ET(B) -- Endothelin and peptide GPCR -- Vasoactive and mitogen-like peptide -- Thermostabilization of ET(B) -- Structures of ET-1-bound and bosentan-bound ET(B) receptor -- Ligand recognition and conformational changes of ET(B) for signal transduction.

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Mode of access: World Wide Web.

4779 Henry Stewart Talks


Cellular signal transduction.
Endothelins--Physiological effect.
Endothelins--Receptors.
G proteins--Receptors.
Bosentan.
Endothelin-1--chemistry.
Endothelin-1--metabolism.
Endothelin-1--pharmacology.
Ligands.
Protein Conformation.
Receptor, Endothelin B--chemistry.
Receptor, Endothelin B--metabolism.
Receptors, Endothelin.
Receptors, G-Protein-Coupled.
Signal Transduction.
Vasoconstriction--drug effects.