Green, Rachel. <br/><br/>
Chemistry of peptide bond formation  [electronic resource] / 
Rachel Green. 
 - London :  Henry Stewart Talks,  2008. 
 - 1 online resource (1 streaming video file (63 min.) :  color, sound). 
 - Mechanisms of ribosome function : insights into protein synthesis,  2056-452X .
 - Henry Stewart talks.  Biomedical & life sciences collection.  Mechanisms of ribosome function : insights into protein synthesis. .
<br/><br/> Animated audio-visual presentation with synchronized narration.  Title from title frames. 
<br/><br/>Contents: Fundamental processes during protein synthesis -- Peptidyl transfer catalysis by RNA-rich active site -- Ribosome structure solution provided new insights -- Peptide bond formation and peptide release -- Active site of the ribosome -- Universally conserved nucleotides of the active site -- Affinity tag purification of mutant ribosomes -- Active site mutations and rates of peptidyl transfer -- A-site substrates: tRNA vs. puromycin -- "Uninduced" state of ribosome and P-site substrate -- A-site substrates-induced conformational changes -- Peptide release activity of variant ribosomes -- RF catalysis in the large subunit -- RF conserved amino acids in bacteria -- Consequences of RF1 site-directed mutations -- Nucleophile partitioning -- Mutants that lost water specificity -- RF components functioning in activating hydrolysis -- Regulation of translation post-initiation. 
<br/><br/> Access restricted to subscribers. 
<br/><br/><br/>Mode of access: World Wide Web. 
<br/><br/><label>Publisher. No.: </label>1744  Henry Stewart Talks 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Protein Biosynthesis.<br/>Ribosomal Proteins.<br/>Ribosomes.