Anti TNF therapy in rheumatoid arthritis [electronic resource] / Marc Feldmann.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
- Anti-TNF therapy in rheumatoid arthritis
Animated audio-visual presentation with synchronized narration.
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Contents: Immunological basis of rheumatoid arthritis (RA) -- Up-regulated cytokine expression is of major importance in RA -- Analysis of the disordered regulation shows that TNF blockade restored normal cytokine and destructive molecule levels and thus defined TNF as a therapeutic target -- Animal models of arthritis -- Clinical trials -- TNF has major input into leucocyte recruitment, it is thus the body's fire alarm -- TNF blockade and Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriasis, psoriatic arthritis and juvenile RA -- This represents the first major use for monoclonal antibodies in chronic diseases.
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Mode of access: World Wide Web.
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