Medicinal chemistry of nucleic acids [electronic resource] / edited by Li-He Zhang, Zhen Xi, Jyoti Chattopadhyaya.

Contributor(s): Material type: TextTextSeries: Wiley series in drug discovery and developmentPublication details: Hoboken, N.J. : Wiley, c2011.Description: xxvi, 428 p., [8] p. of plates : ill. (some col.)Subject(s): Genre/Form: DDC classification:
  • 615/.19 22
LOC classification:
  • RS400 .M438 2011eb
Online resources:
Contents:
Recent advances in carbocyclic nucleosides : synthesis and biological activity / Jianing Wang, Ravindra K. Rawal, and Chung K. Chu -- Structures and functions of nucleic acids modified with S, Se, and Teand complexed with small molecules / Wen Zhang, Jia Sheng, and Zhen Huang -- Unraveling of the NAD cyclizing and calcium signaling functions of human CD38 / Hon Cheung Lee -- DNA and RNA binding small molecules / Shibo Li and Zhen Xi -- G-quadruplex DNA and its ligands in anticancer therapy / Zhi-shu Huang ... [et al.] -- Molecular modeling in nucleic acid targeted drug design / Lidan Sun ... [et al.] -- Structure of 10-23 DNAzyme in complex with the target RNA in silico : a progress report on the mechanism of RNA cleavage by DNA enzyme / Oleksandr Plashkevych and Jyoti Chattopadhyaya -- Labeling oligonucleotides towards the biomedical probe / Il Joon Lee and Byeang Hyean Kim -- Locked nucleic acid oligonucleotides towards clinical application / Rakesh N. Veedu and Jesper Wengel -- The pharmacokinetics researches of nucleic acid drugs / Shengqi Wang -- Inducible RNAi and drug target validation / Wei Xiong ... [et al.] -- SiRNA : the specificity and off-target effects -- Quan Du, Huang Huang, Zicai Liang.
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Includes bibliographical references and index.

Recent advances in carbocyclic nucleosides : synthesis and biological activity / Jianing Wang, Ravindra K. Rawal, and Chung K. Chu -- Structures and functions of nucleic acids modified with S, Se, and Teand complexed with small molecules / Wen Zhang, Jia Sheng, and Zhen Huang -- Unraveling of the NAD cyclizing and calcium signaling functions of human CD38 / Hon Cheung Lee -- DNA and RNA binding small molecules / Shibo Li and Zhen Xi -- G-quadruplex DNA and its ligands in anticancer therapy / Zhi-shu Huang ... [et al.] -- Molecular modeling in nucleic acid targeted drug design / Lidan Sun ... [et al.] -- Structure of 10-23 DNAzyme in complex with the target RNA in silico : a progress report on the mechanism of RNA cleavage by DNA enzyme / Oleksandr Plashkevych and Jyoti Chattopadhyaya -- Labeling oligonucleotides towards the biomedical probe / Il Joon Lee and Byeang Hyean Kim -- Locked nucleic acid oligonucleotides towards clinical application / Rakesh N. Veedu and Jesper Wengel -- The pharmacokinetics researches of nucleic acid drugs / Shengqi Wang -- Inducible RNAi and drug target validation / Wei Xiong ... [et al.] -- SiRNA : the specificity and off-target effects -- Quan Du, Huang Huang, Zicai Liang.

Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.

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